PS222. Ketamine Exerts a Prolonged Reduction in Suicidal Ideation Independent of its Antidepressant Effects
نویسندگان
چکیده
s | 81 of 10000 lux would have much less impact on Indian subjects. 2. Ethnicity – in both studies the subjects were born and spent considerable time in their own respective country. 3. Cultural variations in the food consumed usually by the subjects in respective countries.
منابع مشابه
Ketamine rapidly relieves acute suicidal ideation in cancer patients: a randomized controlled clinical trial
This study was designed to examine the rapid antidepressant effects of single dose ketamine on suicidal ideation and overall depression level in patients with newly-diagnosed cancer. Forty-two patients were enrolled into the controlled trial and randomized into two groups: ketamine group and midazolam group. Patients from the two groups received a sub-anesthetic dose of racemic ketamine hydroch...
متن کاملThe Effect of Intravenous Ketamine in Suicidal Ideation of Emergency Department Patients
INTRODUCTION Suicidal ideation is an emergent problem in the Emergency Department (ED) that often complicates patient disposition and discharge. It has been shown that ketamine possesses fast acting antidepressant and anti-suicidal effects. This study was conducted to examine the effects of a single intravenous bolus of ketamine on patients with suicidal ideations in ED. METHODS Forty-nine su...
متن کاملNeural Correlates of Suicidal Ideation and Its Reduction in Depression
BACKGROUND The neural correlates of suicidal ideation and its reduction after treatment are unknown. We hypothesized that increased regional cerebral glucose metabolism in the infralimbic cortex (Brodmann area 25), amygdala, and subgenual anterior cingulate cortex would be associated with suicidal ideation and its reduction after ketamine infusion. METHODS Medication-free patients (n=19) with...
متن کاملRapid Resolution of Suicidal Ideation after a Single Infusion of an NMDA Antagonist in Patients with Treatment-Resistant Major Depressive Disorder
Objective—Suicidal ideation is a medical emergency, especially when severe. Little research has been done on pharmacological interventions that could address this problem. Ketamine, an Nmethyl-D-aspartate (NMDA) antagonist, has been reported to have antidepressant effects within hours. We examined the effects of a single dose of ketamine on suicidal ideation in subjects with treatment-resistant...
متن کاملKetamine as a fast acting antidepressant: current knowledge and open questions.
Several recent studies have shown that a single intravenous subanesthetic dose of ketamine, a NMDA receptor antagonist, exerts rapid antidepressant effects in patients with treatment refractory mood disorders and reduces suicidal ideation. Those insights have fueled tremendous excitement in the efforts to elucidate the mechanism underlying ketamine's antidepressant properties in animal models o...
متن کامل